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Neuro-Ophthalmologic Manifestations of a paraneoplastic Syndrome and Testicular Carcinoma
Neurol 52:864-867, Bennett,J.L.,et al, 1999
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Article Abstract
The authors report two patients with testicular cancer who exhibited supranuclear gaze disorders as a manifestation of a paraneoplastic brainstem encephalomyelitis. In the first patient, neuro- ophthalmic dysfunction was accompanied by a prominent limbic encephalitis whereas in the second patient, an unusual, mixed pendular and jerk nystagmus was manifested. Neuroimaging revealed an enhancing hypohtalamic mass in the first patient and was negative in the second. Blood from both patients contained an antibody previously reported in a patients with limbic encephalitis and testicular cancer.
 
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carcinoma of testis
down-beat nystagmus
down-beat nystagmus,primary position of gaze
encephalitis,brainstem
gaze palsy,supranuclear
gaze palsy,vertical
hypothalamus
hypothalamus,damage to
limbic encephalitis
MRI
MRI,abnormal
neuroophthalmology
nystagmus
nystagmus,pendular
oculogyric crisis
remote effect of cancer on the nervous system

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